Regenerative

Collagen Biostimulators

An anti-aging pathway that rejuvenates the skin from within, by restoring your own collagen.

SessionUnder an hour
CourseSpaced 3–4 months
Results lastUp to 2 years
Collagen Biostimulators at The Astell Clinic

The key to rejuvenation

Collagen production starts to decline in our twenties, causing fine lines, wrinkles and loss of elasticity. Biostimulation helps reverse this by prompting the body to rebuild its own collagen.

Creams and supplements have limited effect because they don’t fix the drop in production. Biostimulation does — it prompts the body to make its own collagen.

What happens beneath the skin

Injected biocompatible materials trigger a healing response that boosts fibroblasts, the cells that make collagen, gradually strengthening the skin’s structure.

Unlike temporary fillers, which address superficial wrinkles and volume loss, biostimulators enhance the underlying collagen matrix, producing benefits that can last for years.

The appointment
  • Consultation — an initial assessment determines suitability.
  • Injection — typically completed in under an hour, with topical anaesthetic to ease discomfort.
  • Recovery — some redness, swelling or bruising, usually resolving within days.
What it delivers
  • Improved skin quality — firmer, more elastic skin with reduced wrinkles and fine lines.
  • Natural results — enhancement occurs gradually, never abruptly.
  • Non-surgical — minimally invasive, with no cuts and no extended downtime.
Where it is used

Facial volume. Cheeks, temples and jawline restoration.

Body. Neck, décolletage, hands and other areas depending on the treatment.

Considerations
  • Suitability — best for moderate skin laxity or volume loss; not recommended with severe allergies or auto-immune conditions.
  • Sessions — multiple sessions spaced three to four months apart are often needed.
  • Maintenance — periodic follow-ups sustain the effect.
Risks

Common. Minor swelling and bruising at injection sites.

Rare. Persistent lumps, allergic reactions or granuloma formation — which is precisely why administration should be by a qualified doctor.

Products we use

Sculptra

USA

A poly-L-lactic acid (PLLA) collagen biostimulator from the USA that gradually boosts the skin’s own collagen, improving firmness, elasticity, texture and volume with a natural look. Results build progressively and can last up to 2 years, depending on the individual.

Price
24,900THB/vial
Treatment detail
Treatment Process
The doctor assesses your face, skin and concerns to plan the areas and amount, then injects Sculptra after numbing.
Treatment Areas
Common treatment areas include the cheeks, temples, and other areas affected by collagen or volume loss, depending on the doctor’s assessment.
Before Treatment
Avoid Alcohol 24 hrs before treatment
After Treatment
Follow the doctor’s aftercare instructions. Massage of the treated areas after treatment according to the instructions. Avoid excessive pressure or rubbing of the treated areas while they heal.
Downtime
Mild swelling, redness, tenderness, or bruising may occur after treatment and usually gradually subside during the healing process.
Recommended Sessions
Usually 2 vials, with a follow-up within 3-6 months for the best result. Results can last up to 2 years and even one session helps; the doctor will confirm the details at consultation.

Ellanse

the Netherlands

A collagen-stimulating injectable from the Netherlands: PCL microspheres in a CMC gel. The gel gives an immediate lift and volume, while the biodegradable PCL supports structure and stimulates collagen over time. Results last approximately 1-1.5 years, depending on the individual.

1cc
29,900THB
2cc
24,900THB/cc
Treatment detail
Treatment Process
The doctor assesses your face, skin and any volume loss or mild sagging to plan treatment, then carefully injects Ellansé after numbing.
Treatment Areas
Ellansé may be injected around the ligaments that support the face, giving a natural-looking lift and better contours with an appropriate amount.
Before Treatment
Avoid Alcohol 24 hrs before treatment
After Treatment
Follow the aftercare instructions. Avoid excessive pressure or rubbing of the treated areas while they heal.
Downtime
Mild swelling, redness, tenderness, or bruising may occur after treatment and usually gradually subside during the healing process.
Recommended Sessions
Treatment frequency varies depending on individual concerns and treatment goals. The doctor will recommend the appropriate amount and treatment plan during your consultation.

Radiesse

USA

A calcium hydroxylapatite (CaHA) collagen biostimulator from the USA — a biocompatible mineral similar to that in bones and teeth. It gives structure and volume while stimulating collagen over time, improving contour, definition, firmness and skin quality. Results can last up to approximately 2 years, depending on the individual.

Price
24,900THB/box
Treatment detail
Treatment Process
The doctor assesses your face, skin and concerns to choose the amount and technique, then injects Radiesse after numbing.
Treatment Areas
Common treatment areas include the cheeks, jawline, chin, lower face, and other areas requiring structural support, depending on the doctor’s assessment.
Before Treatment
Avoid Alcohol 24 hrs before treatment
After Treatment
Avoid excessive pressure or rubbing of the treated areas while they heal.
Downtime
Mild swelling, redness, tenderness, or bruising may occur after treatment and usually gradually subside during the healing process.
Recommended Sessions
1-3 sessions every 3-6 months; the exact number depends on your concerns, areas and goals, and the doctor will advise at consultation.

Profhilo

Italy

A high-concentration hyaluronic acid (HA) injectable from Italy that spreads through the tissue to improve hydration, firmness and elasticity — without filler-like volume. Results typically last around 9-12 months.

Price
18,900THB/box
Treatment detail
Treatment Process
The doctor assesses the skin condition and treatment areas before administering Profhilo through multiple injection points.
Treatment Areas
Common areas include the face, neck, and other areas with reduced hydration or skin elasticity, depending on the doctor’s assessment. Using 5 points of injections techniques.
Before Treatment
Avoid Alcohol 24 hrs before treatment
After Treatment
Keep the treated areas clean and avoid excessive pressure or rubbing.
Downtime
Small bumps, mild redness, swelling, or bruising may occur at the injection points and usually settle as the skin heals.
Recommended Sessions
1-3 sessions every 4-8weeks apart is commonly recommended for optimal results, followed by maintenance according to individual needs.

Juvelook

South Korea

A collagen-stimulating injectable from South Korea combining PDLLA, which gradually boosts natural collagen, with non-cross-linked HA for hydration. It improves texture, fine lines, enlarged pores and overall skin quality. Results build progressively and last approximately 9-12 months, depending on the individual.

Price
16,900THB/vial
Treatment detail
Treatment Process
The doctor assesses the skin condition and treatment concerns before determining the appropriate injection technique and treatment areas.
Treatment Areas
Common treatment areas include the face, under-eye area, and other areas requiring improvement in skin quality, depending on the doctor’s assessment.
Before Treatment
Avoid Alcohol 24 hrs before treatment
After Treatment
Keep the treated areas clean and avoid excessive pressure or rubbing.
Downtime
Mild redness, swelling, tenderness, bruising, or small temporary bumps may occur after treatment and usually gradually settle.
Recommended Sessions
1-3 sessions every 4-8weeks apart is commonly recommended for optimal results, followed by maintenance according to individual needs.

Therafill

South Korea

A purified atelocollagen injectable from South Korea, processed to reduce the part of collagen linked to immune reactions. It helps skin quality, texture and volume, especially in delicate areas such as under the eyes. Results last approximately 6–9 months, depending on the individual.

Price
15,900THB/box
Treatment detail
Treatment Process
The doctor assesses the skin condition and treatment area before carefully injecting Therafill into the selected areas.
Treatment Areas
Common treatment areas include the under-eye area and other areas with fine lines or superficial volume loss, depending on the doctor’s assessment.
Before Treatment
Avoid Alcohol 24 hrs before treatment
After Treatment
Keep the treated areas clean and avoid excessive pressure or rubbing.
Downtime
Mild swelling, tenderness, or bruising may occur after treatment and usually gradually subside during the healing process.
Recommended Sessions
Maintenance may be recommended approximately every 9 months. The exact frequency varies depending on individual concerns and treatment goals
The entrance arch at The Astell Clinic
The waiting nook, with artwork and velvet armchairs
The archway through to the waiting area
Reception, with the clinic's awards and certificates behind the desk
The reception room seen from the seating area
Reception and the award shelf from the left
Seating beside the reception desk
The waiting sofa against the timber slat wall
The consultation lounge, opening to the garden
The consultation lounge from the desk
The corridor to the treatment rooms
Reading table in the waiting area
The vanity area outside the treatment rooms
A treatment room, prepared
The twin treatment room
The IV and wellness lounge
A treatment in progress
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